Endocrine Abstracts

Introduction: Hyponatraemia is defined as serum sodium concentration <135 mmol/l. It is the most common electrolyte disorder encountered in clinical practise. It is associated with an increase in mortality and length of stay, independent of diagnosis and clinical variables. Despite this it is often inadequately investigated and poorly managed. As a number of endocrine conditions can cause hyponatraemia, endocrinologists often have the necessary clinical skills and expertis...

Introduction: Hyponatraemia is defined as serum sodium concentration <135 mmol/l. It is the most common electrolyte disorder encountered in clinical practise (1). Proton pump inhibitors (PPI’s) are commonly prescribed in the UK, and the indication and duration of treatment is often not reviewed.Methods: A retrospective audit was performed of patients admitted to The Great Western Hospital (GWH) with a serum sodium of 127 mmol/l or less on admiss...

Introduction: Hyponatraemia is defined as serum sodium concentration <135 mmol/l. It is the most common electrolyte disorder encountered in clinical practise. It is associated with an increase in mortality and length of stay, independent of diagnosis and clinical variables. Despite this it is often inadequately investigated and poorly managed.Methods: A retrospective audit was performed of patients admitted to The Great Western Hospital (GWH) serum s...

Introduction: Hyponatraemia is common and associated with significant morbidity and mortality. However, it’s often not recognised as a serious diagnosis and therefore inadequately investigated and poorly managed. An audit of the management of patients admitted to The Great Western Hospital (GWH) with hyponatraemia confirmed these problems. A hyponatraemia guideline was produced in order to improve diagnosis, investigation, and management of patients with hyponatraemia.</p...

Case History: A 52 year old man presented in 2009 with a gradual loss of peripheral vision associated with headaches. Examination confirmed bi-temporal hemianopia. Further investigation revealed elevated prolactin levels and pituitary MRI showed evidence of large pituitary tumour. A diagnosis of macroprolactinoma was made and cabergoline was commenced. Given resistance to medical treatment, the patient required two surgical resections (2011 and 2013) and radical radiotherapy (...

Introduction: We present the case of a clinically functioning gonadotroph adenoma in a pre-menopausal woman with abdominal pain, bilateral multi-cystic ovaries and fibromatosis. To our knowledge, this is the first case of fibromatosis associated with a functioning gonadotroph adenoma.Case: A 36 year old female presented on three occasions with acute abdominal pain. She was previously well and had two normal pregnancies. On the first admission, she underw...